Evans is fit too, but I doubt van Gaal changes Smalling and Rojo while they're playing well.
Southampton's press will take Carrick out of the game and Wanyama will likely dominate Mata. The matchup on the wings with Tadic and Mane vs. Valencia and Young looks bad too. Schneiderlin out is big though. They don't really have the depth to cope with that, so our forwards should get chances.
Can't see us winning this, but we've made a lot of progress in the last few games. Just need the attack to click now.